Amazon S3 Transfer Acceleration is a feature that speeds up the transfer of large files over the public internet to and from Amazon S3. It uses Amazon CloudFront's globally distributed edge locations to accelerate transfers and can improve the performance of your applications by up to 300%. To use S3 Transfer Acceleration, you will need to enable it for your S3 bucket and use the Accelerate endpoint when uploading or downloading objects. You can use the AWS Management Console or the AWS API to enable and disable S3 Transfer Acceleration and monitor its performance. 

S3 Transfer Acceleration is a fully managed service, and is easy to use and integrate with other AWS services. It is a cost-effective way to quickly transfer large files to and from S3 and can be used for a variety of workloads, including data migration, backup and restore, and data lake ingress and egress. 

CloudFront is a CDN that speeds up the delivery of static and dynamic content, while S3 is an object storage service that provides scalable, durable, and secure storage for data and objects. S3 Transfer Acceleration speeds up the transfer of large files over the public internet to and from S3. These services can be used together or separately to store, manage, and deliver data and content in the cloud.